Clinical Application of the Levothyroxine Absorption Test in the Diagnosis of Pseudo-Malabsorption

We present a variation and clinical application of the Levothyroxine Absorption Test (LAT) in the identification of pseudo-malabsorption of levothyroxine in uncontrolled hypothyroidism, for which there is no current gold standard protocol, and a variety of methods proposed in the literature. The LAT was conducted over 5days with thyroid function tests conducted pre-LAT, then at day 1 and 5. The thyroid stimulating hormone levels became completely suppressed indicating that there had been previous non-compliance with medication.